Goran Kaluderovic

Tätigkeitsbereiche

LEHRGEBIETE

• Anorganische Chemie
• Biologische Chemie
• Biotechnologie
• Ökologische Stoffwandlungsprozesse

FORSCHUNGSBEREICHE

• Koordinationschemie
• Bioanorganische Chemie
• Bioorganische Chemie
• Bionanochemie

Publikationen

Ausgewählte Publikationen und Referenzen

Publikationen
ORCID iD          Researchgate-Profil                      Google Scholar


Ausgewählte Publikationen

• Eichhorn, T., Kolbe, F., Mišić, S., Dimić, D., Morgan, I., Saoud, M., Milenković, D., Marković, Z., Rüffer, T., Dimitrić Marković, J., Kaluđerović, G.N. (2023): Synthesis, Crystallographic Structure, Theoretical Analysis, Molecular Docking Studies, and Biological Activity Evaluation of Binuclear Ru (II)-1-Naphthylhydrazine Complex, Int. J. Mol. Sci., 24, 689.
• Predarska, I., Saoud, M., Drača, D., Morgan, I., Komazec, T., Eichhorn, T., Mihajlović, E., Dunđerović, D., Mijatović, S., Maksimović-Ivanić, D., Hey-Hawkins, E., Kaluđerović, G.N. (2022): Mesoporous Silica Nanoparticles Enhance the Anticancer Efficacy of Platinum (IV)-Phenolate Conjugates in Breast Cancer Cell Lines, Nanomaterials, 12, 3767.
• Knežević, N.Ž., Ilić, N., Kaluđerović, G.N. (2022): Mesoporous Silica Nanoparticles for pH-Responsive Delivery of Iridium Metallotherapeutics and Treatment of Glioblastoma Multiforme, Inorganics 10, 250.
• Bensing, C., Mojić, M., Bulatović, M., Edeler, D., Pérez-Quintanilla, D., Gómez-Ruiz, S., Maksimović-Ivanić, D., Mijatović, S., Kaluđerović, G.N. (2022): Effect of chain length on the cytotoxic activity of (alkyl-ω-ol) triphenyltin (IV) loaded into SBA-15 nanostructured silica and in vivo study of SBA-15~Cl| Ph₃Sn(CH₂)₈OH, Biomat. Adv. 140, 213054.
• Drača, D., Edeler, D., Saoud, M., Dojčinović, B.,  Dunđerović, D., Đmura, G., Maksimović-Ivanić, D., Mijatović, S., Kaluđerović, G.N. (2021): Antitumor potential of cisplatin loaded into SBA-15 mesoporous silica nanoparticles against B16F1 melanoma cells: in vitro and in vivo studies, J. Inorg. Biochem. 217, 111383
• Arlt, S., Petković, V., Ludwig, G., Eichhorn, T., Lang, H., Rüffer, T., Mijatović, S., Maksimović-Ivanić, D., Kaluđerović, G.N. (2021): Arene Ruthenium(II) Complexes Bearing the κ-P or κ-P,κ-S Ph₂P(CH₂)₃SPh Ligand. Molecules 26, 1860.
• Jänicke, P., Lennicke, C., Meister, A., Seliger, B., Wessjohanna, L.A., Kaluđerović, G.N. (2021): Fluorescent spherical mesoporous silica nanoparticles loaded with emodin: Synthesis, cellular uptake and anticancer activity, Mat. Sci. Eng. C 119, 111619
• Smolko, L., Smolková, R., Samoľová, E., Morgan, I., Saoud, M., Kaluđerović, G.N. (2020): Two isostructural Co(II) flufenamato and niflumato complexes with bathocuproine: analogues with a different cytotoxic activity, J. Inorg. Biochem. 210, 111160.
• Edeler, D., Drača, D., Petković, V., Natalio, F., Maksimović-Ivanić, D., Mijatović, S., Schmidt, H., Kaluđerović, G.N. (2019):  Impact of the mesoporous silica SBA-15 functionalization on the mode of action of Ph₃Sn(CH₂)₆OH,  Mat. Sci. Eng. C 100, 315-322.
• Edeler D, Arlt S, Petković V, Ludwig G, Drača D, Maksimović-Ivanić D, Mijatović S, Kaluđerović GN. (2018), Drug delivery system for emodin based on mesoporous silica SBA-15 mesoporous silica: Preparation, characterization and in vitro study, J Inorg Biochem. 180, 155–162.
• Krajnović T., Maksimović-Ivanić D., Mijatović S., Drača D., Wolf K., Edeler D., Wessjohann L.A., Kaluđerović G.N. (2018), Drug Delivery System for Emodin Based on Mesoporous Silica SBA-15, Nanomaterials 8, pii: E322
• Hübner, D., Kaluđerović, M.R., Gómez-Ruiz, S. and Kaluđerović, G.N. (2017), Anionic chlorido(triphenyl)tin(IV) bearing N-phthaloylglycinato or 1,2,4-benzenetricarboxylato 1,2-anhydride ligands: potential cytotoxic and apoptosis-inducing agents against several types of cancer, Chem. Biol. Drug Des. 89, 628–633.
• Kaluđerović, G.N., Abbas, M., Kautz, H.C., Wadaan, M.A.M., Lennicke, C., Seliger, B. and Wessjohann, L.A. (2017), Methionine and seleno-methionine type peptide and peptoid building blocks synthesized by five-component five-center reactions, Chem. Commun. 53, 3777–3780.
• Ludwig, G., Mojić, M., Bulatović, M.Z., Mijatović, S., Maksimović-Ivanić, D., Steinborn, D. and Kaluđerović, G.N. (2016). Biological Potential of Halfsandwich Ruthenium(II) and Iridium(III) Complexes. Anticancer Agents Med Chem. 16, 1455–1460.
• Bensing, C., Mojić, M., Gómez-Ruiz, S., Carralero, S., Dojčinović, B., Maksimović-Ivanić, D., Mijatović, S. and Kaluđerović G.N. (2016): Evaluation of functionalized mesoporous silica SBA-15 as a carrier system for Ph3Sn(CH2)3OH against A2780 ovarian carcinoma cell line, Dalton Trans. 45, 18984–18993.
• Edeler, D., Kaluđerović, M.R., Dojčinović, B., Schmidt, H. and Kaluđerović G.N. (2016): SBA-15 mesoporous silica particles loaded with cisplatin induce senescence in B16F10 cells, RSC Advances. 6, 111031–111040.
• Kaluđerović, G. N., Krajnović, T., Momcilovic, M., Stosic-Grujicic, S., Mijatović, S., Maksimović-Ivanić, D., Hey-Hawkins, E. (2015). Ruthenium(II) p-cymene complex bearing 2,2’-dipyridylamine targets caspase 3 deficient MCF-7 breast cancer cells without disruption of antitumor immune response, J. Inorg. Biochem. 153, 315–321.
• Bulatović, M. Z., Maksimović-Ivanić, D., Bensing, C., Gómez-Ruiz, S., Steinborn, D., Schmidt, H., Mojić, M., Korać, A., Golić, I., Pérez-Quintanilla, D., Momčilović, M., Mijatović, S. and Kaluđerović, G. N. (2014). Organotin(IV)-Loaded Mesoporous Silica as a Biocompatible Strategy in Cancer Treatment, Angew. Chem. Int. Ed. 53, 5982–5987; Angew. Chem. 126, 6092–6097.
• Pantelić, N., Zmejkovski, B.B., Trifunović-Macedoljan, J., Savić, A., Stanković, D., Damjanović, A., Juranić, Z., Kaluđerović, G. N. and Sabo, T. J. (2013). Gold(III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N'-diacetate, J. Inorg. Biochem. 128C, 146–153.
• Ludwig, G., Mijatović, S., Ranđelović, I., Bulatović, M., Miljković, D., Maksimović-Ivanić, D., Korb, M., Lang, H., Steinborn, D. and Kaluđerović, G. N. (2013). Biological activity of neutral and cationic iridium(III) complexes with κP and κP,κS coordinated Ph2PCH2S(O)xPh (x = 0–2) ligands, Europ. J. Med. Chem. 69C, 216–222.
• Maksimović-Ivanić, D., Mijatović, S., Mirkov, I, Stošić-Grujičić, S.D., Miljković, D., Sabo, T.J., Trajković, V. and Kaluđerović, G.N. (2012). Melanoma tumor inhibition by tetrachlorido(O,O’-dibutyl-ethylenediamine-N,N’-di-3-propionate)platinum(IV) complex: in vitro and in vivo investigations, Metallomics 4, 1155–1159.
• Sanchez-Munoz, S., Gómez-Ruiz, S., Perez-Quintanilla, D., Morante-Zarcero, S., Sierra, I., Prashar, S., Paschke, R. and Kaluđerović, G.N. (2012). Preliminary study of the anticancer applications of mesoporous materials functionalized with the natural product betulinic acid; ChemMedChem, 7, 670–679.
• Kaluđerović, G.N., Dietrich, A., Kommera, H., Kuntsche, J., Mäder, K., Mueller, T. and Paschke, R. (2012). Liposomes as vehicles for water insoluble platinum-based potential drug: 2-(4-(tetrahydro-2H-pyran-2-yloxy)-undecyl)propane-1,3-diamminedichloro-platinum(II), Europ. J. Med. Chem. 54, 567–572.
• Gómez-Ruiz, S., Ceballos-Torres, J., Prashar, S., Fajardo, M., Žižak, Ž,. Juranić, Z. D. and Kaluđerović, G. N. (2011). One ligand different metal complexes: Biological studies of titanium(IV), tin(IV) and gallium(III) derivatives with the 2,6-dimethoxypyridine-3-carboxylato ligand, J. Organomet. Chem. 696, 3206–3213.
• Kaluđerović, G. N., Pérez-Quintanilla, D., Sierra, I., Prashar, S., Hierro, I., Žižak, Ž., Juranić, Z. D., Fajardo, M. and and Gómez-Ruiz, S. (2010). Study of the influence of the metal complex on the cytotoxic activity of titanocene-functionalized mesoporous materials. J. Mater. Chem. 20, 806–814.
• Kaluđerović, G. N., Pérez-Quintanilla, D., Žižak, Ž,. Juranić, Z. D. and Gómez-Ruiz, S (2010). Improvement of cytotoxicity of titanocene-functionalized mesoporous materials by the increase of the titanium content. Dalton Trans. 2597–2608.
• Kaluđerović, G. N., Kommera, H., Hey-Hawkins, E., Paschke, R. and Gómez-Ruiz, S. (2010). Synthesis and biological applications of ionic triphenyltin(IV) chloride carboxylate complexes with exceptionally high cytotoxicity, Metallomics 2, 419–428.
• Pérez-Quintanilla, D., Gómez-Ruiz, S., Žižak, Ž,. Sierra, I., Prashar, S., Hierro, I. Fajardo, M., Juranić, Z. D. and Kaluđerović, G. N. (2009). A new generation of anticancer drugs. Mesoporous materials modified with titanocene complexes. Chem. – Europ. J. 22, 5588–5597.
• Kaluđerović, G. N., Kommera, H., Schwieger, S., Schmidt, H., Paethanom, A., Kunze, M., Paschke, R. and Steinborn, D. (2009). Preparation, DFT calculations and antitumoral investigations of some platinum(IV) complexes with O,O’-dialkyl-ethylenediamine-N,N’-di-3-propanoate (R2eddp) ligands, Dalton Trans. 10720–10726.

Reviews

• Kaluđerović, G. N., Paschke, R. (2011). Anticancer metallotherapeutics in preclinical Development, Curr. Med. Chem. 18, 4738–4752.
• Gómez-Ruiz, S., Maksimović-Ivanić, D., Mijatović, S., Kaluđerović, G. N. (2012). On the discovery, mechanism and use of cisplatin and metallocenes in anticancer chemotherapy, Bioinorg. Chem. Appl. Article ID 140284, 1–14.
• Knežević, N. Ž., Kaluđerović, G. N. (2017). Silicon-based nanotheranostics, Nanoscale 9, 12821–12829.
• Mijatović S., Bramanti A., Nicoletti, F., Faragone, P., Kaluđerović, G. N., Maksimović-Ivanić, D. (2018). Naturally occuring compounds in differentiation based therapy of cancer, Biotechnol. Adv. 36, 1622–1632.
• Zmejkovski, B.B., Pantelić, N.Đ., Kaluđerović, G.N. (2022): Palladium (II) complexes: Structure, development and cytotoxicity from cisplatin analogues to chelating ligands with N stereocenters, Inorg. Chim. Acta 120797.

Buchkapitel

• Kaluđerović, G. N., Schmidt, H., Steinborn, D., Sabo, T. J. (2008). Inorganic Biochemistry: Research Progress. In J. G. Hughes, A. J. Robinson, (Ed.), From synthesis to antitumoral activity of platinum(II) and platinum(IV) complexes with bis(carboxyalkylamino)ethane and -propane ligands (S. 305–326). NY: Nova Science Publishers, Inc. Hauppauge. ISBN: 978-1-60456-708-3.
• Wessjohann, L. A., Kaluđerović, G. N., Neves Filho, R. A. W. et al. (2013). Science of Synthesis: Multicomponent Reactions 1. In T. J. J. Müller (Ed.), Further Components Carboxylic Acid and Amine (Ugi Reaction) (S. 415–502). Stuttgart: Georg Thieme Verlag KG. ISBN: 9783131728616.
• Wessjohann, L. A., Schreckenbach, H. F., Kaluđerović, G. N. (2015). Science of Synthesis: Biocatalysis in Organic Synthesis 2. In K. Faber, W.-D. Fessner, N. J. Turner, N. J. (Eds.), Enzymatic C-Alkylation of Aromatic Compounds (S. 177–211). Stuttgart: Georg Thieme Verlag KG. ISBN: 9783131741417.

Lebenslauf

1994-1999 Chemiestudium, Fakultät für Chemie, Universität Belgrad, Belgrad, Jugoslawien

2002 Magister, Fakultät für Chemie, Universität Belgrad, Belgrad, Serbien und

2005 Dissertation, Fakultät für Chemie, Universität Belgrad, Belgrad, Serbien undMontenegro

2006–2008 Alexander von Humboldt–Stipendiat bei Prof. Dr. D. Steinborn, Institut für Chemie, Martin-Luther-Universität Halle-Wittenberg, Deutschland

05/2014 Habilitation, Naturwissenschaftliche Fakultät II - Chemie, Physik und Mathematik, Martin-Luther-Universität Halle-Wittenberg, Deutschland

Auszeichnungen
2007 Forschungspreis der Martin-Luckner-Stiftung für Entwicklung neuer Antitumorwirkstoffe
2008 Medaille der Serbischen Chemischen Gesellschaft für herausragende Leistungen und Erfolge in der Wissenschaft im Jahr 2008